APPLICATIONS & PROCESSES

1. APPLICATIONS FOR 96-WELL MAGNETIC TIP COMB

   • DNA and RNA Extraction: The 96-well Magnetic Tip comb applications in DNA and RNA extraction protocols. Magnetic beads coated with nucleic acid-binding agents are added to the sample lysates. The comb is then used to attract and immobilize these beads within the wells, allowing for efficient separation of nucleic acids from other cellular components. This method is widely utilized in research and clinical laboratories for various downstream applications such as PCR, sequencing, and genotyping.
   • Protein Purification: The 96-well magnetic tip comb is also employed in protein purification workflows. Magnetic beads conjugated with affinity ligands, such as antibodies or tags specific to the target protein, are added to the samples. The comb is used to capture the beads, allowing for selective binding and isolation of the desired proteins. This technique enables high-throughput protein purification, making it suitable for screening assays, protein-protein interaction studies and structural biology experiments.
   • Immunoprecipitation (IP) Assays: Immunoprecipitation is a technique used to isolate specific proteins or protein complexes from complex biological samples. Magnetic bead-based IP assays utilize the 96-well magnetic tip comb to capture antibody-bound protein complexes. This approach facilitates the study of protein-protein interactions, post-translational modifications, and protein localization in a high-throughput manner.
   • Cell-Based Assays: In cell-based assays, the 96-well magnetic tip comb is utilized for various applications, including cell separation, cell sorting and cell culture. By immobilizing magnetic beads coated with cell-specific ligands or antibodies, researchers can isolate specific cell populations from heterogeneous samples, allowing for downstream analysis or cell-based assays.
   • Drug Discovery and Screening: The high-throughput capabilities of the 96-well magnetic tip comb make it an indispensable tool in drug discovery and screening workflows. By utilizing magnetic bead-based assays, researchers can screen large compound libraries for drug candidates, assess drug-target interactions, and evaluate compound efficacy and toxicity in a rapid and efficient manner.

   
2. INDUSTRIES UTILIZING 96-WELL MAGNETIC TIP COMB

   • Biotechnology and Pharmaceutical Industry: The biotechnology and pharmaceutical sectors extensively utilize the 96-well magnetic tip comb in various stages of drug discovery, development and quality control. From target identification and validation to lead optimization and preclinical studies, magnetic bead-based assays enable researchers to streamline workflows, increase throughput and improve assay sensitivity and specificity.
   • Clinical Diagnostics: In clinical diagnostics laboratories, the 96-well magnetic tip comb plays a crucial role in nucleic acid-based diagnostic assays, including PCR-based tests, next-generation sequencing (NGS) and molecular diagnostics. These assays are used for the detection and quantification of infectious diseases, genetic disorders, cancer biomarkers and other clinically relevant targets.
   • Academic and Research Institutions: Academic and research laboratories utilize the 96-well magnetic tip comb for a wide range of molecular biology, biochemistry and cell biology experiments. These laboratories conduct basic research, applied research, and translational studies across various disciplines, including genetics, immunology, microbiology and oncology.